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Generic Protonix - Pantoprazole is a proton pump inhibitor (PPI) that suppresses the final step in gastric acid production by forming a covalent bond to two sites of the (H+, K+)-ATPase enzyme system at the secretory surface of the gastric parietal cell. This effect is dose-related and leads to inhibition of both basal and stimulated gastric acid secretion irrespective of the stimulus. The binding to the (H+, K+)-ATPase results in a duration of antisecretory effect that persists longer than 24 hours.
Active Ingredients: Pantoprazole sodium
Other Ingredients: calcium stearate, crospovidone, hydroxypropyl methylcellulose, iron oxide, mannitol, methacrylic acid copolymer, polysorbate 80, povidone, propylene glycol, sodium carbonate, sodium lauryl sulfate, titanium dioxide, and triethyl citrate.

Generic Protonix - Pantoprazole is a prescription drug that is used to treat and maintain healing of erosive acid reflux disease, also known as erosive GERD (breaks in the lining of the esophagus), and relieve associated symptoms that may include frequent and persistent heartburn and stomach acid backup. Most patients heal within 8 weeks of treatment. Doctors may prescribe Generic Protonix - Pantoprazole beyond 8 weeks to maintain healing or to prevent a recurrence of your symptoms. Controlled studies did not extend beyond 12 months.

Take Generic Protonix - Pantoprazole exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.
Take each dose with a full glass of water. Generic Protonix - Pantoprazole can be taken with or without food. Do not crush, chew, or split the tablets. Swallow them whole. Generic Protonix - Pantoprazole is specially formulated to release the medication slowly in the body.
Do not stop taking Generic Protonix - Pantoprazole even if you begin to feel better. Your symptoms may improve before the condition is fully treated. STORAGE Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed.

Talk to your doctor before taking Generic Protonix - Pantoprazole if you have liver disease. You may not be able to take Generic Protonix - Pantoprazole, or you may require a dosage adjustment or special monitoring during treatment if you have liver disease.
Pantoprazole is in the FDA pregnancy category B. This means that it is unlikely to be harmful to an unborn baby. Do not take Generic Protonix - Pantoprazole without first talking to your doctor if you are pregnant. It is not known whether Generic Protonix - Pantoprazole passes into breast milk. Do not take Generic Protonix - Pantoprazole without first talking to your doctor if you are breast-feeding a baby.

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

Seek emergency medical attention if an overdose is suspected. Symptoms of a pantoprazole overdose are not known.

In general, Generic Protonix - Pantoprazole was well tolerated in clinical studies. Adverse effects were not dose related. The following side effects were experienced by 1% or more of patients taking Generic Protonix - Pantoprazole and had incidence greater than placebo and/or nizatidine:

• Diarrhea
• Rash
• Hyperglycemia
• Flatulence

Safety and effectiveness in pediatric patients have not yet been established.
No dosage adjustment is recommended based on age, renal impairment, or for patients undergoing hemodialysis.
Safety and effectiveness for long-term treatment (greater than 16 weeks) has not yet been determined.

Before taking Generic Protonix - Pantoprazole, tell your doctor if you are taking any of the following medicines:

• ketoconazole (Nizoral),
• ampicillin (Omnipen, Principen), or
• iron (Feosol, Mol-Iron, Fergon, Femiron, others).

You may not be able to take Generic Protonix - Pantoprazole, or you may require a dosage adjustment or special monitoring during your treatment if you are taking any of the medicines listed above.
Drugs other than those listed here may also interact with Generic Protonix - Pantoprazole. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.

Keep all appointments with your doctor and the laboratory. Your doctor may order certain lab tests to check your body's response to Generic Protonix - Pantoprazole. Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.