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Generic Arava-Leflunomide is an oral, disease-modifying antirheumatic prescription drug (DMARD), which helps improving rheumatoid arthritis (RA) symptoms such as joint swelling and tenderness. But unlike many symptom relievers that only help relieve pain and swelling, Generic Arava-Leflunomide actually helps slow the progression of joint damage caused by rheumatoid arthritis.
Generic Arava-Leflunomide is one of several types of therapies that interfere with cell turnover. Methotrexate interferes with an enzyme called dihydrofolate reductase, whilst leflunomide interferes with an enzyme called dihydroorotate dehydrogenase. This results in inhibition of synthesis of Pyrimidines - key components of DNA.
Active Ingredients: Leflunomide.
Inactive Ingredients: Silica colloidal anhydroustalc, crospovidone, macrogol, maize starch, titanium dioxide, lactose monohydrate, hypromellose, magnesium stearate, povidone.

Generic Arava-Leflunomide is used in the treatment of rheumatoid arthritis. It reduces the pain, stiffness, inflammation, and swelling associated with this disease, improves physical function, and staves off the joint damage that ultimately results.

Take Generic Arava-Leflunomide tablets by mouth. Follow the directions on the prescription label. Swallow the tablets with a drink of water. You can take Generic Arava-Leflunomide with food or milk. Take your doses at the same time every day. Do not take your medicine more often than directed. Continue to take your medicine even if you feel better. Do not stop taking your medicine unless your prescriber or health care professional tells you to discontinue taking it. The usual dose is 100 mg daily for the first 3 days, followed by 20 mg daily. Doctors may reduce the dose to 10 mg daily if side effects appear.
Keep out of the reach of children in a container that small children cannot open. Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from moisture and light. Throw away any unused medicine after the expiration date.

You must not take Generic Arava-Leflunomide if you are pregnant or a woman of childbearing age not using reliable contraception. If you suspect or find out that you are pregnant while taking Generic Arava-Leflunomide call you health care provider right away. After stopping Generic Arava-Leflunomide treatment you must complete the drug elimination procedure before becoming pregnant because Generic Arava-Leflunomide stays in the body a long time. You should not breast-feed if you are taking Generic Arava-Leflunomide.
You'll also need to avoid Generic Arava-Leflunomide if it gives you an allergic reaction.
Theoretically, Generic Arava-Leflunomide may interfere with your body's ability to fight off infection. The drug is therefore not recommended for people with cancer, bone marrow problems, severe infections, AIDS, or any other immune system problems. You should also avoid immunization with live vaccines while taking Generic Arava-Leflunomide

Take the missed dose as soon as possible. Should you forget to take the scheduled dosage until the following day, skip it and proceed with the next one. Generic Arava-Leflunomide must not be double dosed.

If symptoms of Overdosage are suspected, consult your doctor for the proper medical action. Symptoms of an Generic Arava-Leflunomide overdose may include diarrhea, abdominal pain, blood problems, and liver problems.

Side effects you should report to your doctor as soon as possible are:
• dark yellow or brown urine
• diarrhea, especially if severe or does not stop
• difficulty breathing or shortness of breath
• dizziness
• fever or chills, cough or sore throat
• increases in blood pressure, especially if you are being treated for high blood pressure
• numbness, pain, or tingling in an arm, hand, leg, or foot
• pain in the stomach or abdomen
• skin rash or hives
• ulcers of the mouth or difficulty or pain on swallowing
• unusual bleeding or bruising, pinpoint red spots on the skin, nose bleeds or bleeding gums
• unusual tiredness or weakness
• vomiting
• yellowing of eyes or skin

Side effects that usually do not require medical attention are:
• Back pain
• Hair loss
• Heartburn
• Skin rash
• Stomach pain
• Unexplained weight loss

Tell to your doctor if these side effects continue or are bothersome.

Tell your doctor of all nonprescription and prescription medication you may use, especially :
• Cholestyramine (Questran, Prevalite, LoCHOLEST),
• methotrexate (Rheumatrex),
• rifampin (Rifadin, Rimactane).

Drugs other than those listed here may also interact with Generic Arava-Leflunomide. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.
Refrain from drinking alcohol while taking this medication. It can increase the chance of having liver problems. Do not have immunizations or vaccinations without consulting your doctor first while under medication or after treatment of Generic Arava-Leflunomide.

Tell your doctor your medical history especially: If you have liver disease or a history of hepatitis, a history of significant alcohol use, kidney disease, an immune system disease, recently received a live vaccine, poor bone marrow function, or a current or chronic infection. Generic Arava-Leflunomide should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. Consult your doctor before breast-feeding. Discuss with your doctor the use of alcohol while taking Generic Arava-Leflunomide. Alcohol and Generic Arava-Leflunomide can both be damaging to the liver.